Malvern Instruments' latest product will debut at PMEC/CPHI Pharmaceutical Show

Malvern Instruments will bring many newest instrument products to attend the 2012 World Pharmaceutical Machinery, Packaging Equipment & Materials China Exhibition (P-MEC) at Shanghai New International Expo Center from June 26th to 28th (Malware Booth No: W3A22 ). Malvern will provide a full range of pharmaceutical solutions from development to quality control, including the Mastersizer 3000 laser diffraction particle size analyzer, Zetasizer NanoZS nanoparticle size and Zeta potential and molecular weight analyzer, Insitec online particle size analyzer and Spraytec real-time spray particle size analyzer.

On the second day of the show, Wednesday, June 27th, 9:30 am, Malvern will hold the "Welcome to Multi-detector Gel Permeation Chromatography GPC/SEC in Biological and Medical Fields" Seminar at W3F80. , Welcome to participate, on-site participating customers will have the opportunity to get the exquisite gifts provided by Malvern Instruments.

Malvern has more than 30 years of experience in particle characterization analysis, serving the entire process of rapid product development from early formulation screening to key quality control parameters: its particle size measurement system allows formulators to predict drug release kinetics, and the image analysis system ensures assessment Effects of particle size and shape of drug intermediates or excipients on product morphology and bioavailability; Rheology/Zeta potential measurement predicts the stability of a given formulation; Online particle characterization system based on FDA-approved process analysis technology (PAT ) Track drug grinding, grading, spray drying and granulation processes and closed system process control.

The size, shape, quantity, distribution and other factors of the drug particles are critical to the performance and efficacy of the drug formulation. Therefore, in the process of drug development, production, and clinical testing, the measurement and control of drug particle parameters must be ensured at all times. For example, active ingredients and excipients in nasal spray drug products are typically dissolved or suspended in the formulation. The parameters such as the size and shape of the spray particle directly affect the delivery, dissolution, and absorption of the drug components. Rheology is another important tool in the pharmaceutical industry. The rheological properties determine the key performance characteristics of many formulations, including creams, suspensions, and solutions.

In the overall solution provided by Malvern, the Mastersizer 3000 measures the widest particle size range up to the present of the world's widest 10nm to 3500μm. It is suitable for the determination of wet and dry samples with high accuracy and reproducibility. The ZetasizerNanoZS can accurately detect high The concentration of sample particles; Morphologi G3 provides statistically significant particle size and shape information. The Kinexus rotary rheometer provides a comprehensive and accurate analysis of the rheological properties of materials. Viscotek GPC gel permeation chromatography system can quickly and reliably characterize the molecular weight and molecular weight distribution of each type of polymer.

Malvern's products are widely used in particle characterization, molecular structure determination, rheological properties measurement, etc., can quickly and efficiently characterize the physical and chemical properties of pharmaceutical ingredients, help to shorten the drug development time, optimize formulation ingredients, enhance the stability of the formula Sex and quality, determination of bioavailability, provision of standard illustrations, protection of intellectual property rights, control of homogeneity of content and increased awareness of products and production processes, continue to meet the growing demand for highly sensitive and versatile analytical technologies in the pharmaceutical industry. . In addition, the company's unique QSpec certification system can provide a full set of documents and certificates that fully comply with FDA, MCA, GMP and COS international certification requirements.

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